— Koneksa Resources —
Publications and Patents
Pre-Prints (as of May 5, 2025)
Solicited Cough Sound Analysis For Tuberculosis Triage Testing: The Coda Tb Dream Challenge Dataset
Sophie Huddart, Vijay Yadav, Solveig K. Sieberts, Larsson Omberg, Mihaja Raberahona, Rivo Rakotoarivelo, Issa N. Lyimo, Omar Lweno, Devasahayam J Christopher, Nguyen Viet Nhung, Theron, William Worodria, Charles Y. Yu, Christine M Bachman, Stephen Burkot, Puneet Dewan, Sourabh Kulhare, Peter M Small, Adithya Cattamanchi, Devan Jaganath, Grandjean Lapierre. Preprint; Posted March 28, 2024.
Manuscripts
A Composite Measurement Concept for Monitoring Cardiac Function in Fabry Disease
Pooja Nandi, Robert Ellis, Jennifer Hiros, Paul Howard, Biliana O, Veleva-Rotse. Orphanet Journal of Rare Diseases 2025; 20:382.
Identifying Concepts Of Physical Activity Which Are Clinically Meaningful To Patients And Care Providers: A Systematic Review Of Qualitative Research
Candice Taguibao, Salma Ajraoui, Jake Centra, Kieran F Reid, Christina Daskalopoulou, Alberto Conde Freniche, Alan L Hamilton, Astrid MH Horstman, Benjamin X Collins, Jessilyn Dunn, Elena S Izmailova. Clinical and Translational Science 2025; 18(4):e70191.
A Dataset Of Solicited Cough Sound For Tuberculosis Triage Testing
Sophie Huddart, Vijay Yadav, Solveig K Sieberts, Larsson Omberg, Mihaja Raberahona, Rivo Rakotoarivelo, Issa N Lyimo, Omar Lweno, Devasahayam J Christopher, Nguyen Viet Nhung, Grant Theron, William Worodria, Charles Y Yu, Christine M Bachman, Stephen Burkot, Puneet Dewan, Sourabh Kulhare, Peter M Small, Adithya Cattamanchi, Devan Jaganath, Simon Grandjean Lapierre. Scientific Data; 2025 11(1):1149.
Digital Measures Development: Lessons Learned From An Expert Workshop Addressing Cross-Therapeutic Area Measures Of Sleep
Piper Fromy, Michael Kremliovsky, Emmanuel Mignot, Mark Aloia, Jonathan Berent, Farah Hasan, Dennis Hwang, Jiat-Ling Poon, Rebecca Malcolm, Christopher Miller, Womba Nawa, Jessie Bakker. Digital Biomarkers 2024; 8(1):132-139.
A Hierarchical Framework For Selecting Reference Measures For The Analytical Validation Of Sensor-Based Digital Health Technologies
Jessie P Bakker, Samantha J McLenahan, Piper Fromy, Simon Turner, Barry T Peterson, Benjamin Vendendriessche, Jennifer C Goldsack. Journal of Medical Internet Research 2025;27:e58956
A Patient Centric Model For Vaso-Occlusive Crises In Sickle Cell Disease — Outcomes Of A Consensus Exercise Conducted Across Patients And Experts
Pooja Nandi, Robert Ellis, Ankita Deshpande. Clinical and Translational Science 2025; 18(4):e70197
V3+ Extends The V3 Framework To Ensure User-Centricity And Scalability Of Sensor-Based Digital Health Technologies
Jessie P Bakker, Roland Barge, Jacob Centra, Bryan Cobb, Chas Cota, Christine C Guo, Bert Hartog, Nathalie Horowicz-Mehler, Elena S Izmailova, Nikolay V Manyakov, Smantha McClenahan, Stéphane Motola, Smit Patel, Oana Paun, Marian Schoone, Emre Sezgin, Thomas Switzer, Animesh Tandon, Willem van den Brink, Srinivasan Vairavan, Benjamin Vandendriessche, Bernard Vrijens, Jennifer C Goldsack. NPJ Digital Medicine 2025; 8:51
Human Factors, Human-Centered Design, And Usability Of Sensor-Based Digital Health Technologies: Scoping Review
Animesh Tandon, Bryan Cobb, Jacob Centra, Elena Izmailova, Nikolay V Manyakov, Smantha McClenahan, Smit Patel, Emre Sezgin, Srinivasan Vairavan, Bernard Vrijens, Jessie P Bakker. Journal of Medical Internet Research 2024; 26:e57628.
Syndication In Science: Curated Collaboration
David B Hurry, Elena S Izmailova, Simon Davies, Olivier Harari, S Aubrey Stoch, John A Wagner. Clinical & Translational Science 2024; 17(12):e70085.
Accelerating Parkinson's Disease Drug Development With Federated Learning Approaches
Amit Khanna , Jamie Adams , Chrystalina Antoniades , Bastiaan R Bloem , Camille Carroll, Jesse Cedarbaum, Joshua Cosman, David T Dexter, Marissa F Dockendorf, Jeremy Edgerton, Laura Gaetano, Erkuden Goikoetxea, Derek Hill, Fay Horak, Elena S Izmailova, Tairmae Kangarloo, Dina Katabi, Catherine Kopil , Michael Lindemann, Jennifer Mammen, Kenneth Marek, Kevin McFarthing, Anat Mirelman, Martijn Mulle, Gennaro Pagano, M Judith Peterschmitt, Jie Ren, Lynn Rochester, Sakshi Sardar, Andrew Siderowf, Tanya Simuni, Diane Stephenson, Christine Swanson-Fischer, John A Wagner, Graham B Jones. NPJ Parkinson’s Disease 2024; 10:225.
Impacts On Study Design When Implementing Digital Measures In Parkinson's Disease-Modifying Therapy Trials
Jennie S. Lavine, Anthony D. Scotina, Seth Haney, Jessie P. Bakker, Elena S. Izmailova, Larsson Omberg. Frontiers in Digital Health 2024; 6:1430994.
Implementing Sensor-Based Digital Health Technologies In Clinical Trials: Key Considerations From The eCOA Consortium
Elena S Izmailova , Danielle Middleton , Reem Yunis , Julia Lakeland , Kristen Sowalsky, Julia Kling , Alison Ritchie , Christine C Guo , Bill Byrom , Scottie Kern. Clinical and Translational Science 2024; 17(11):e70054.
Regulatory Pathways For Qualification And Acceptance Of Digital Health Technology-Derived Clinical Trial Endpoints: Considerations For Sponsors
Jessie Bakker, Elena Izmailova, Aude Clement, Steven Hoffmann, Christopher Leptak, Joseph Menetski, John Wagner. Clinical Pharmacology and Therapeutics 2024; 117(1):56-72.
A Novel Estimator For The Two-Way Partial AUC
Elias Chaibub Neto, Vijay Yadav, Solveig K. Sieberts & Larsson Omberg. BMC Medical Informatics and Decision Making 2024; 24:57.
A Proposed Multi-Domain, Digital Model For Capturing Functional Status And Health-Related Quality Of Life In Oncology
Elena S. Izmailova, John A. Wagner, Jessie P. Bakker, Rachel Kilian, Robert Ellis, Nitin Ohri. Clinical and Translational Science 2024; 17(1):e13712.
The Stepwise Study: Study Protocol For A Smartphone-Based Exercise Solution For People With Parkinson’s Disease (Randomized Controlled Trial)
Sabine Schootemeijer, Nienke M. de Vries, Eric A. Macklin, Kit C.B. Roes, Hilde Joosten, Larsson Omberg, Alberto Ascherio, Michael A. Schwarzschild & Bastiaan R. Bloem. BMC Neurology 2023; 23:323
Study Protocol: A Comparison Of Mobile And Clinic-Based Spirometry For Capturing The Treatment Effect In Moderate Asthma
Elena S Izmailova, Rachel Kilian, Jessie P Bakker, Shawna Evans, Anthony D Scotina, Theodore F Reiss, Dave Singh, John A Wagner. Clinical and Translational Science 2023; 16(11):2112-2122.
Digital Technologies: Innovations That Transform The Face Of Drug Development
Elena S Izmailova, Bilal AbuAsal, Hazem E. Hassan, Anindita Saha, Diane Sephenson. Clinical and Translational Science 2023; 16(8):1323-1330.
Reverse Engineering Of Digital Measures: Inviting Patients To The Conversation
Ieuan Clay, Nele Peerenboom, Dana E Connors, Steven Bourke, Alison Keogh; Katarzyna Wac, Tova Gur-Arie, Justin Baker, Christopher Bull, Andrea Cereatti, Francesca Cormack, Damien Eggenspieler, Luca Foschini, Raluca Ganea, Peter MA Groenen, Nicole Gusset, Elena S Izmailova, Christoph M Kanzler, Lada Leyens, Kate Lyden, Arne Mueller, Julian Nam, Wan-Fai Ng, David Nobbs, Foteini Orfaniotou, Thanneer Malai Perumal; Wojciech Piwko, Anja Ries; Alf Scotland, Nick Taptiklis, John Torous, Beatrix Vereijken, Shuai Xu, Laurenz Baltzer, Thorsten Vetter, Jörg Goldhahn, Steven C Hoffmann. Digital Biomarkers 2023; 7(1):28-44.
Digital Health Technology Derived Measures: Biomarkers Or Clinical Outcome Assessments?
Elena S Izmailova, Charmaine Demanuele, Marie McCarthy. Clinical and Translational Science 2023; 16(7):1113-1120.
Characterization Of Influenza-Like Illness Burden Using Commercial Wearable Sensor Data And Patient-Reported Outcomes: Mixed Methods Cohort Study
Victoria Hunter, Alliston Shapiro, Devika Chawla, Faye Drawnel, Ernesto Ramirez, Elizabeth Phillips, Sara Tadesse-Bell, Luca Foschini, Vincent Ukachukwu. Journal of Medical Internet Research 2023; 25:e41050.
Sensor Integration For Gait Analysis
Yunus Celik, Rodrigo Vitório, Dylan Powell, Jason Moore, Fraser Young, Graham Coulby, James Tung, Mina Nouredanesh, Robert Ellis, Elena S Izmailova, Sam Stuart, Alan Godfrey. Encyclopedia of Sensors and Biosensors 2023; 4:263-283.
Verification, Analytical Validation, And Clinical Validation (V3) Of Wearable Dosimeters And Light Loggers
Manuel Spitschan, Karin Smolders, Benjamin Vandendriessche, Brinnae Bent, Jessie P Bakker, Isaac R Rodriguez-Chavez, Céline Vetter. Digital Health 2022; 8:20552076221144858.
Empowering Drug Development: Leveraging Insights From Imaging Technologies To Enable The Advancement Of Digital Health Technologies
Elena S Izmailova , R Paul Maguire , Timothy J McCarthy , Martijn L T M Müller , Philip Murphy, Diane Stephenson. Clinical and Translational Science 2022; 16(3):383-397.
When Work Hits Home: The Cancer-Treatment Journey Of A Clinical Scientist Driving Digital Medicine
Elena S Izmailova and Robert Ellis. JCO Clinical Cancer Informatics 2022; 6:e2200033.
Sensor Verification And Analytical Validation Of Algorithms To Measure Gait And Balance And Pronation/Supination In Healthy Volunteers
Robert Ellis, Peter Kelly, Chengrui Huang, Andrew Pearlmutter, Elena S. Izmailova. Sensors 2022; 22(16):6275.
Quantifying The Benefits Of Digital Biomarkers And Technology-Based Study Endpoints In Clinical Trials: Project Moneyball
Hiromasa Mori, Stig Johan Wiklund, and Jason Yuren Zhang. Digital Biomarkers 2022; 6(2):36-46.
Considerations For Conducting Bring Your Own “Device” (Byod) Clinical Studies
Charmaine Demanuele, Cynthia Lokker, Krishna Jhaveri, Pirinka Georgiev, Emre Sezgin, Cindy Geoghegan, Kelly H. Zou, Elena S. Izmailova, Marie McCarthy. Digital Biomarkers 2022; 6(2):47-60.
Recommendations For Defining And Reporting Adherence Measured By Biometric Monitoring Technologies: Systematic Review
Iredia M Olaye, Mia P Belovsky, Lauren Bataille, Royce Cheng, Ali Ciger, Karen L Fortuna, Elena S Izmailova, Debbe McCall, Christopher J Miller, Willie Muehlhausen, Carrie A Northcott, Isaac R Rodriguez-Chavez, Abhishek Pratap, Benjamin Vandendriessche, Yaara Zisman-Ilani, Jessie P Bakker. Journal of Medical Internet Research 2022; 24(4):e33537.
Clinical And Immunological Evaluation Of Cat-Allergic Asthmatics Living With Or Without A Cat
Erik R Wambre, Mary Farrington, Veronique Bajzik, Hannah A DeBerg, Marcella Ruddy, Michelle DeVeaux, Pretty Meier, David Robinson, Matt Cantor, Chengrui Huang, Jamie M Orengo, Claire Q Wang, Allen Radin. Clinical and Experimental Allergy 2021; 51(12):1624-1633.
Biometric Monitoring Technologies In Cancer: The Past, Present, And Future
Elena S Izmailova, William A Wood. JCO Clinical Cancer Informatics 2021 5:728-733
Multimodal Biometric Monitoring Technologies Drive The Development Of Clinical Assessments In The Home Environment
Benjamin Vandendriessche, Alan Godfrey, Elena S Izmailova. Maturitas 2021; 151:41-47
Closer To The Patient Means Better Decisions: Wearable Remote Monitoring Of Patients With Covid-19 Lung Disease
Elena S Izmailova, Theodore F Reiss. Clinical and Translational Science 2021; 14(6):2091-2094
Evidence Publication Checklist For Studies Evaluating Connected Sensor Technologies: Explanation And Elaboration
Christine Manta, Nikhil Mahadevan, Jessie P Bakker, Ozen Simal Irmak, Elena S Izmailova, Siyeon Park S, Jiat-Ling Poon, S Shevade, S Valentine, Benjamin Vandendriessche, C Webster, Jennifer S Goldsack. Digital Biomarkers 2021; 5(2):127-147.
Remote Cardiac Safety Monitoring Through The Lens Of The Fda Biomarker Qualification Evidentiary Criteria Framework: A Case Study Analysis
Elena S. Izmailova, William A. Wood, Qi Liu, Vadim Zipunnikov, Dan Bloomfield, Jason Homsy, Steven C. Hoffmann, John A. Wagner, Joseph P. Menetski. Digital Biomarkers 2021; 5(1):103-113.
Fit-For-Purpose Biometric Monitoring Technologies (Biomet): Leveraging The Laboratory Biomarker Experience
Alan Godfrey, Benjamin Vandendriessche, Jessie P. Bakker, Cheryl Fitzer-Attas, Ninad Gujar, Matthew Hobbs, Qi Liu, Carrie A Northcott, Virginia Parks, William A Wood, Vadim Zipunnikov, John A Wagner, and Elena S Izmailova. Clinical and Translational Science 2021; 14(1):62-75.
Remote Digital Monitoring For Medical Product Development
Elena S. Izmailova, John A Wagner, Nadir Ammour, Ninad Amondikar, Andrea Bell-Vlasov, Steven Berman, Dan Bloomfield, Linda S Brady, Xuemei Cai, Roberto A. Calle, Michelle Campbell, Francesca Cerreta, Ieuan Clay, Luca Foschini, Pat Furlong, Rob Goldel, Jennifer S. Goldsack, Peter MA Groenen, Amos Folarin, Jill Heemskerk, Peter Honig, Matthew Hotopf, Tania Kamphaus, Daniel R Karlin, Christopher Leptak, Qi Liu, Husseini Manji, Robert J. Mather, Joseph P Menetski, Vaibhav A. Narayan, Elektra Papadopoulos, Bakul Patel, Bray Patrick-Lake, Jagdeep T Podichetty, Abhishek Pratap, Laurent Servais, Diane Stephenson, Pam Tenaerts, Bruce J Tromberg, Steve Usdin, Srikanth Vasudevan, Vadim Zipunnikov, Steven C Hoffmann. Clinical and Translational Science 2021; 14(1):94-101.
An Evaluation Of Biometric Monitoring Technologies For Vital Signs In The Era Of Covid-19
Christine Manta, Sachin Jain, Andrea Coravos, Dena Mendelsohn, Elena Izmailova. Clinical and Translational Science 2020 13(6):1034-1044.
Remote Fev1 Monitoring In Asthma Patients: A Pilot Study
Chengrui Huang, Elena S Izmailova, Natalie Jackson, Robert Ellis, Gaurav Bhatia, Marcella Ruddy, Dave Singh. Clinical and Translational Science 2020; 14(2):529-535.
Use Of Surface Emg In Clinical Rehabilitation Of Individuals With Sci: Barriers And Future Considerations
Rakesh Pilkar, Kamyar Momeni, Arvind Ramanujam, Manikandan Ravi, Erica Garbarini, Gail F Forrest. Frontiers in Neurology 2020; 11:578559.
Dynamic Margins Of Stability During Robot-Assisted Walking In Able-Bodied Individuals: A Preliminary Study
Arvind Ramanujam, Kamyar Momeni, Manikandan Ravi, Jonathan Augustine, Erica Garbarini, Peter Barrance, Ann M Spungen, Pierre Asselin, Steven Knezevic, Gail F Forrest. Frontiers in Robotics and AI 2020; 7:574365.
Remote Monitoring In Clinical Trials During The Covid-19 Pandemic
Elena S Izmailova, Robert Ellis, and Christopher Benko. Clinical and Translational Science 2020; 13(5):838-841.
Verification, Analytical Validation, And Clinical Validation (V3): The Foundation Of Determining Fit-For-Purpose For Biometric Monitoring Technologies (Biomets)
Jennifer C Goldsack, Andrea Coravos, Jessie P Bakker, Brinnae Bent, Ariel V Dowling, Cheryl Fitzer-Attas, Alan Godfrey, Job G Godino, Ninad Gujar, Elena S Izmailova, Christine Manta, Barry Peterson, Benjamin Vandendriessche, William A Wood, Ke Wil Wang, Jessilyn Dunn. NPJ Digital Medicine 2020; 3:55.
“In-House” Data On The Outside - A Mobile Health Approach
Qinlei Huang, Tami Crumley, Christina Walters, Liesbeth Cluckers, Ingeborg Heirman, Radha Railkar, Gaurav Bhatia, Matthew Cantor, Christopher Benko, Elena S Izmailova, Sylvie Rottey, S Aubrey Stoch. Clinical Pharmacology & Therapeutics 2020 107(4):948-956.
Advancing The Use Of Mobile Technologies In Clinical Trials: Recommendations From The Clinical Trials Transformation Initiative
Philip Coran, Jennifer C Goldsack, Cheryl A Grandinetti, Jessie P Bakker, Marisa Bolognese, E Ray Dorsey, Kaveeta Vasisht, Adam Amdur, Christopher Dell, Jonathan Helfgott, Matthew Kirchoff, Christopher J Miller, Ashish Narayan, Dharmesh Patel, Barry Peterson, Ernesto Ramirez, Drew Schiller, Thomas Switzer, Liz Wing, Annemarie Forrest, Aiden Doherty. Digital Biomarkers 2019 3(3):145-154.
A Systematic Review Of Feasibility Studies Promoting The Use Of Mobile Technologies In Clinical Research
Jessie P Bakker, Jennifer C Goldsack, Michael Clarke, Andrea Coravos, Cynthia Geoghegan, Alan Godfrey, Matthew G Heasley, Daniel R Karlin, Christine Manta, Barry Peterson, Ernesto Ramirez, Nirav Sheth, Antonia Bruno, Emilia Bullis, Kirsten Wareham, Noah Zimmerman, Annemarie Forrest, William A Wood. NPJ Digital Medicine 2019; 2:47.
Big Data From Small Devices: The Future Of Smartphones In Oncology
Juhi M Purswani, Adam P Dicker, Colin E Champ, Matt Cantor, Nitin Ohri. Seminars in Radiation Oncology 2019; 29(4):338-347.
Continuous Monitoring Using A Wearable Device Detects Activity‐induced Heart Rate Changes After Administration Of Amphetamine
Elena S Izmailova, Ian L. McLean, Greg Hather, David Merberg, Jason Homsy, Matthew Cantor, Dmitri Volfson, Gaurav Bhatia, Eric D Perakslis, Christopher Benko, John A Wagner. Clinical and Translational Science 2019; 12(6):677-686.
Evaluation Of Wearable Digital Devices In A Phase I Clinical Trial
Elena S Izmailova, Ian L McLean, Gaurav Bhatia, Greg Hather, Matthew Cantor, David Merberg, Eric D Perakslis, Christopher Benko, John A Wagner. Clinical and Translational Science 2019; 12(3):247-256.
Wearable Devices In Clinical Trials: Hype And Hypothesis
Elena S Izmailova, John A Wagner, Eric D Perakslis. Clinical Pharmacology & Therapeutics 2018; 104(1):42-52.
Assessing Changes In The Activity Levels Of Breast Cancer Patients During Radiation Therapy
Colin E Champ, Nitin Ohri, Rainer J Klement, Matthew Cantor, Sushil Beriwal, Scott M Glaser, Ryan P Smith. Clinical Breast Cancer 2017; 18(1):E1-E6.
Abstracts
Content Validity of Digital Motor Assessments and Accompanying Electronic Patient-Reported Outcomes in a Parkinson’s Disease Human Factors Study.
Larsson Omberg, Jeffrey Zhang, Jennie S Lavine, Anthony Scotina, John Wagner, Elena Izmailova, Juanita Yim, Jessie Bakker. International Conference on Alzheimer’s and Parkinson’s Diseases and Related Neurological Disorders; 2025.
Applicability of Self-Administered Measures Derived From MDS-UPDRS Parts 2 and 2 to Evaluate Parkinson’s Disease Progression: Interim Analysis
Larsson Omberg, Jennie S Lavine, Jessie Bakker, Anthony Scotina, Shawna Evans, Gabriella Stephenson, Marissa Dockendorf, Robert Ellis, Olivier Harari, David Hurry, Susi Lee, Eric Mangin, Jie Ren, Peter Schmidt, Matthew Wipperman, Ramon Rodriguez, Peter Lewitt, John Wagner. International Conference on Alzheimer’s and Parkinson’s Diseases and Related Neurological Disorders; 2025.
Reliability of Digital Measures in Parkinson’s Disease and Their Implications for Sample Size Calculations
Jennie Lavine, Anthony Scotina, Seth Haney, Elena Izmailova, Larsson Omberg. Movement Disorders 2024; 39(suppl 1):1237.
Cardiac Biomarkers in Fabry Disease
Pooja Nandi, Robert Ellis, Biliana Veleva-Rotse, Jennifer Hiros, Paul Howard. WORLDSymposium; 2024 (not published online; available on request).
Study Design Considerations for Digital Assessments in Parkinson’s Disease Clinical Trials
Jennie Lavine, Anthony Scotina, Elena Izmailova, Larsson Omberg. Value in Health 2024; 27(suppl 1):MT33.
Objective Physical Activity Measures to Predict Hospitalizations Among Patients With Cancer Receiving Chemoradiotherapy
Anthony D. Scotina, Jennie S. Lavine, Elena S. Izmailova, Rafi Kabarriti, Keyur J. Mehta, Madhur Garg, Shalom Kalnicki, and Nitin Ohri. JCO Oncology Practice 2023; 19(suppl 11):592.
Actigraphy Wear Compliance Across CNS Disorders
Jennie Lavine, Andrew Pearlmutter, Kam Momeni, Robert Ellis. Movement Disorders 2023; 38(suppl 1):1769.
Analytical Validity of a Walk Detection and Gait Algorithm in Different Wear Configurations
Peter Kelly, Robert Ellis, Chengrui Huang, Arvind Ramanujam, Samuel Thorpe, Andrew Cohen. The International Society for CNS Clinical Trials and Methodology 19th Annual Scientific Meeting; 2023.
Capability of Accelerometers in Wearable Devices for Measurement of Postural Tremor, Gait and Balance, and Nocturnal Scratching
Peter Kelly, Andrew Cohen, Robert Ellis. The International Society for CNS Clinical Trials and Methodology 18th Annual Scientific Meeting; 2022.
Parkinson’s Disease Functional Impacts Digital Instrument (PD-FIDI): Studies Preceding Clinical Validation
Andrew Pearlmutter, Nicholas Wong, Molly Follette Story, Riliang Zheng, Robert Ellis, Peter Kelly, M Judith Peterschmitt. Movement Disorders 2021; 36(suppl 1):1298.
Clinical Trial Digital Endpoint Development: Patient and Provider Perspectives on the Most Impactful Functional Aspects of Parkinson’s Disease
Andrew Pearlmutter, Julia C Nantes, Nir Giladi, Fay B Horak, Roy N Alcalay, Jeffrey M Hausdorff, Tanya Simuni, Max A Little, Ashwani Jha, Sylvie Bozzi, Rob Arbuckle, M Judith Peterschmitt. European Journal of Neurology 2021; 28(suppl 1):EPO-637.
Daily Step counts to Predict Hospitalizations During Chemoradiotherapy for Head and Neck Cancer
Elena S. Izmailova, Andrew Cohen, Rafi Kabarriti, Jeremy Eichler, Chengrui Huang, Nitin Ohri. Journal of Clinical Oncology 2021; 39(suppl 15):1571.
Compliance Analysis for Remote Spirometry in Subjects with Mild to Moderate Asthma
Chengrui Huang, Peter Kelly, Marcella K Ruddy, Elena S Izmailova, and Robert Ellis. American Journal of Respiratory and Critical Care Medicine 2021; 203:A1733.
Feature development of digital measures for the finger tapping task
Peter Kelly, Robert Ellis. The International Society for CNS Clinical Trials and Methodology 18th Annual Scientific Meeting; 2021.
Analytical Validity of a New Algorithm to Identify Walking Periods in Continuous Wrist-worn Accelerometer
Peter Kelly, Robert Ellis, Chengrui Huang. Innovations in Clinical Neuroscience; 2020.
Development of an Algorithm for the Evaluation of Gait and Balance Impairments in CNS Disorders
Robert Ellis, Peter Kelly, Chengrui Huang. The International Society for CNS Clinical Trials and Methodology 17th Annual Scientific Meeting; 2020.
Comparison of Accelerometers Used for Measurement of Upper Body Postural Tremor, and Gait and Balance
Peter Kelly, Chengrui Huang, Robert Ellis. Movement Disorders 2020; 35(suppl 1):1415.
Analytical Validity and Operational Tolerance of a New Algorithm in Healthy Individuals to Calculate Gait and Balance Feature Scores from an iPhone Application
Robert Ellis, Peter Kelly, Chengrui Huang. Movement Disorders Society Virtual Congress 2020; LBA8.
Speech, Posture, and Gait Results of a Phase 2, Double-Blind Study to Evaluate TAK-831 in Adults With Friedreich Ataxia
Greg Hather, Jonathan Norton, Dmitri Volfson, Adam Vogel, Fay Horak, Matthew Johnson, Elena S Izmailova, Jennifer Farmer, David Lynch, Hao Wang. International Ataxia Research Conference 2019; A244.
Daily Step Counts to Predict Hospitalizations During Concurrent Chemoradiotherapy for Solid Tumors
Elena Izmailova, Chengrui Huang, Matthew Cantor, Robert Ellis, Nitin Ohri. Journal of Clinical Oncology 2019; 37(suppl 27):293.
Long-Term Proteasome Inhibition (LTPI) in Patients (PTS) With Newly Diagnosed Multiple Myeloma (NDMM): US MM-6, A Real-World (RW) Study Transitioning from Bortezomib (BTZ) to Ixazomib (IXA)
Robert M. Rifkin, Habte A. Yimer, Stephen J. Noga, Sudhir Manda, Ruemu Birhiray, Christopher Yasenchak, Roger Lyons, Peter Kelly, Eric Chojnicki, Presley Whidden, Bingxia Wang, Brittany Demers, Larry Dollar, Ralph Boccia. 24th Congress of European Hematology Association 2019; PF729.
Mobile Health Technology Captures “In-House” Data On The Outside: An Assessment with Pharmacological Intervention
Gaurav Bhatia, Qinlei Huang, Tami Crumley, Christina Walters, Liesbeth Cluckers, Ingeborg Heirman, Lori Mixson, Sylvie Rottey, Matthew Cantor, Christopher Benko, S Aubrey Stoch. American Society for Clinical Pharmacology and Therapeutics 2019; 105(suppl 1):S5-S121.
Validating Remote FEV1 Monitoring in Moderate Asthmatics to Increase Study Power
Gaurav Bhatia, Natalie Jackson, Marcella Ruddy, Dave Singh. American Journal of Respiratory and Critical Care Medicine 2018; 197:A3934.
Patents
Patents Awarded
Method and device for high accuracy measurements of steps and strides agnostic to wear position
Peter Kelly, Robert Ellis, Chengrui Huang
US Patent Number: 11,307,050; Patent Award Date: April 19, 2022
Movement analysis method and apparatus
Peter Kelly, Robert Ellis, Chengrui Huang
US Patent Number: 11,397,193; Patent Award Date: July 26, 2022
Health monitoring system with modular processing architecture
Robert Ellis, Peter Kelly, Josh Feldman, Juanita Yim
US Patent Number: 11,646,104; Patent Award Date: May 9, 2023
Patents in Application
Highly configurable health monitoring system with the ability to support multiple studies comprising multiple schedules to centrally collect and process data from multiple data sources.
Robert Ellis, Peter Kelly, Joshua Feldman, Juanita Yim
A highly configurable health monitoring system that dynamically adjusts the schedule of assessments based on defined criteria or external events
Robert Ellis, Peter Kelly, Joshua Feldman, Juanita Yim
A health monitoring system that centrally configures assessments and data sources across selectable subsets of deployed devices
Robert Ellis, Peter Kelly, Joshua Feldman, Juanita Yim
Method and device for high accuracy detection and measurement of pronation and supination motions
Peter Kelly, Robert Ellis