Prioritizing the Front Line of Clinic Research

Prioritizing the Front Line of Clinic Research

I am fortunate to have the opportunity to travel to multiple site initiation visits and trainings for clinical research studies each year.  Meeting with the incredibly dedicated study teams is an invaluable experience as I am able to hear from the people who support the front line of clinical research.  During a recent training, I sat down with a research coordinator who seemed to be stretched very thin.  Noticing this, we took a step back to talk through her hesitations.

Tech Tonics: Chris Benko, From Fortune 100 to Fortune Seeker

Tech Tonics: Chris Benko, From Fortune 100 to Fortune Seeker

Chris Benko first joined Merck when he was but a lad of eighteen, rising through the ranks in HR and talent management to become one of the youngest VPs in the history of the organization, at the age of 34.

But instead of continuing his ascending career into the senior ranks of biopharma, Chris opted instead to scratch the entrepreneurial itch and, after several years in Merck venture capital group, he founded a new company and left Merck to run it.

ActiGraph Launches CentrePoint Toolkit to Provide Technology Framework for Home-­ based Healthcare Solutions

ActiGraph Launches CentrePoint Toolkit to Provide Technology Framework for Home-­ based Healthcare Solutions

Pensacola, FL – Nov 15, 2016 -­ ActiGraph, a leading provider of clinical-­grade wearable activity and sleep monitoring solutions, has announced the launch of the CentrePoint technology toolkit, which enables clients to leverage the company’s ecosystem of hardware and software tools in the development of proprietary remote patient monitoring (RPM) systems and other home healthcare delivery solutions.

What’s the sweet spot for digital health collaborations with pharma clinical studies?

What’s the sweet spot for digital health collaborations with pharma clinical studies?

This week’s news that Takeda Pharmaceuticals inked a deal with Koneksa Health, a digital health startup that uses wearables and connected devices to gather patient data, reinforces the point that pharma companies have found a place for digital health tools in drug development. Koneksa Health CEO Chris Benko said he views the natural place for the use of these technologies in clinical studies either in early phases or as an exploratory addition in later phases in a phone interview with MedCity News.

Takeda and Koneksa Health Announce Strategic Collaboration to Use Digital Health Tools in Clinical Trials

Takeda and Koneksa Health Announce Strategic Collaboration to Use Digital Health Tools in Clinical Trials

Cambridge, Mass. , and New York, NY, USA,  November 7, 2016 – Takeda Pharmaceutical Company Limited (TSE: 4502) (“Takeda”) and Koneksa Health, Inc. (“Koneksa”), an early stage company focused on the integration of real world data into clinical research, today announced an ongoing strategic collaboration to utilize new digital health tools in clinical trials.  

Patient-Centered Approach to Clinical Trials

Patient-Centered Approach to Clinical Trials

There is an exciting paradigm shift happening in industry sponsored clinical trials, particularly for the patients contributing to research. Prior to joining Koneksa I worked for one of the highest enrolling clinical ophthalmology sites in the country, where over 25 studies were conducted at a time. I’ve experienced first-hand the significant burden placed on participants in clinical trials, with study visits lasting well over six hours.

Innovations Announced at CES

Innovations Announced at CES

 We weren’t able to make it to CES this year, but we were keeping a close eye on the new digital health announcements to see if anything really impressed us.  Amongst many new wearables and sensors that seemed to bring marginal improvement, there were a few hardware / software announcements that we are looking forward to testing and bringing to our customers. 

Making Sense of Evidence

Making Sense of Evidence

On January 30th of this year President Obama announced a $215 million precision medicine initiative to improve health and disease. This initiative is part of a broad trend towards disease prevention and treatment that takes into account individual differences in people’s genes, environments, and lifestyles. Fulfilling the promise of precision medicine will depend on high quality evidence linking patient measurements and health. But what makes for high quality evidence?

Breaking Down a Gold Standard

Breaking Down a Gold Standard

One of the common challenges we see at Koneksa is the tendency of the research community to gravitate toward evaluating novel measures or endpoints for concurrence with older and very limited ‘gold standards.’ Previously I discussed the lack of an underlying conceptual framework for activity measures that rely on patient reported outcomes (PROs).  However similar challenges also emerge with more objective performance measures.

DIY: Get To Know Your Target Customer

DIY: Get To Know Your Target Customer

Product starts and ends with design.  Many times, the design process starts with a series of questions:

  • What do you want to build? (Product, service, etc.)
  • Who is building something similar? 
  • Who are you building it for?

From here, every line you draw and decision you make has to be optimized for the best user experience. Understanding your target customer is the key for building a product people will value.

Exercise Hacks: Are You Measuring Your Health?

Exercise Hacks: Are You Measuring Your Health?

As an engineer (by training) and physician-scientist, I need to quantify things.

With websites like FitDay, I can easily track my food intake, and with devices like glucometers and ketone meters, I can use my blood glucose and ketone levels to assess my physiologic response to food, exercise, and my morning drive with just a prick of the finger. Exercise, however, has eluded me for years, both professionally and personally.

Newcomer To Healthcare - Perspectives a Year On

Newcomer To Healthcare  - Perspectives a Year On

I joined Koneksa to run technology in May 2014. I’ve spent many years building systems for financial services and, to some, extent consumer industries. I joined healthcare motivated to apply my skills after watching how technology was changing the conversation in my father’s last months of life. The journey has not disappointed.

In this post I share two themes I’ve noticed over the last year. 

It Is Time To Prioritize Study Participants

It Is Time To Prioritize Study Participants

Recently we attended the Clinical Trials and Internet of Things forum, held in Boston’s Longwood medical area. It was an exciting two days of biopharma, technology companies and CROs coming together to discuss the potential of wearables, sensors, and mobile devices to transform clinical research.  However one speaker, Jack Whelan, struck us as a unique voice in the conversation.