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- Koneksa Resources -

Resource Library

Koneksa is constantly driving the scientific development and application of digital biomarkers forward. Whether it’s through articles, white papers, webinars, or other forms of communication, Koneksa takes the role of thought leader in this space very seriously.

Explore our content to gain a deeper understanding of the role of digital biomarkers in clinical trials.

Posters

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POSTER

Koneksa WORLD 2024 Cardiac biomarkers in Fabry Disease


The composite measurement concept outlined here may be used as the foundation for future analytical validation, usability, and clinical validation seeking to capture the progression of cardiac function in FD.

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POSTER

Development of an algorithm for the evaluation of gait and balance impairments in CNS disorders

The new algorithm may be of use in studies of (central nervous system) CNS disorders, such as Parkinson’s disease.

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POSTER

Parkinson’s Disease Functional Impacts Digital Instrument (PD-FIDI)_ Studies Preceding Clinical Validation

Summarize the findings from three developmental studies of the Parkinson’s Disease Functional Impacts Digital Instrument (PD-FIDI).

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POSTER

Study design considerations for digital assessments in Parkinson’s disease clinical trials

Here, we develop recommendations for digital assessment implementation in PD clinical trials.

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POSTER

Validating Remote FEV1 Monitoring in Moderate Asthmatics to Increase Study Power

Mobile measurements are equivalently reliable to in-clinic measurements.

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POSTER

Compliance Analysis for Remote Spirometry in Subjects with Mild to Moderate Asthma

Remote spirometry data collection is feasible in studies recruiting asthma patients.

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POSTER

Capability of accelerometers in wearable devices for measurement of postural tremor...

Motor symptoms in patients with movement disorders are traditionally measured using clinician and patient reported outcome measures such as the MDS-UPDRS.

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POSTER

Comparing accuracy of accelerometers for measurement of gait and balance, and upper body postural tremor

The iPhone 8 Plus is suitable for measuring acceleration of gait & balance and postural tremor.

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POSTER

Feature development of digital measures for the finger tapping task

The MDS-UPDRS[1] is considered the gold standard for assessing symptom severity in Parkinson’s disease. This scale assesses multiple aspects of daily living.

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POSTER

Analytical validity of a walk detection and gait algorithm in different wear configurations

10 healthy subjects performed a series of walking tests while wearing 6 ActiGraph GT9X Link devices concurrently, one for each of 6 wear positions.

White Papers

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WHITE PAPER

Implementing Digital Endpoints in CNS Clinical Trials

The global disease burden of central nervous system (CNS) conditions is high and on the rise, and this increase is forecasted to continue as the global population ages.



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WHITE PAPER

Beyond the Clinic: Remote Spirometry Data Collection in Respiratory Diseases

Spirometry is a key technology to assess lung function; it provides important data for the diagnosis and monitoring of disease and for the measurement of treatment efficacy.

Fact Sheets

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FACT SHEET

Solutions Overview

Koneksa provides readily deployable, established digital biomarkers using a suite of measures and works with sponsors to develop novel design concepts tailored to specific clinical trial needs.




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FACT SHEET

Neuroscience Toolkit

Deploy reliable, accurate digital biomarkers that are designed and developed with input from patients and clinicians.






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FACT SHEET

Respiratory Fact Sheet

Our remote respiratory measures enable you to confidently evaluate the impact of your treatment and make cost-effective go/no-go decisions earlier using convenient and frequent data collection and real-time transmission in our configurable platform.



Let's Collabrate

Interested in integrating digital measures into your study or accessing our experience in a specific indication?

Contact us - our experts are ready to partner with you
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